Tokio Tani
Research highlight
We are analyzing biological roles of noncoding RNAs (ncRNAs) in a wide
range of cellular reactions, such as pre-mRNA splicing, nuclear structure
formation, chromatin remodeling and genome stability, using fission yeast
and cultured mammalian cells. NcRNAs are defined as RNAs with no significant
protein-coding capacity. We have recently revealed that ncRNAs transcribed
from the centromere regions have essential roles in chromosome segregation.
A new paradigm of “ncRNA regulation in chromosome segregation” is now emerging.
In addition, we are trying to breed novel fission yeast strains suitable
for brewing rice (or sweet potato) shochu, a traditional Japanese distilled sprit, which is generally brewed by
budding yeast Saccharomyces cerevisiae.
Résumé
1980 - 1982: Graduate School of Medical Sciences, Tsukuba University
1982 - 1987: Researcher, Bioscience Laboratory, Sankyo Co., Ltd.
1987 - 1991: Assistant professor, Faculty of Science, Kyushu University
1991 - 2001: Associate professor, Faculty of Science, Kyushu University
2001 - 2023: Professor, Faculty of Science, Faculty of Advanced Science
and Technology, Kumamoto University
Contact information
Tel:
(+81) 096-342-3461 or 3311
Email: ttani(at)sci.kumamoto-u.ac.jp
Address:
2-39-1 Kurokami, Chuo-ku, Kumamoto, 860-8555 JAPAN
Kurokami South campus
Faculty of Science Building 1, Room C316
PhD., Specially appointed professor
RNA molecular biology
Department of Basic Research
Select publications
DDX41 coordinates RNA splicing and transcriptional elongation to prevent
DNA replication stress in hematopoietic cells. Satoru Shinriki, Mayumi
Hirayama, Akiko Nagamachi, Akihiko Yokoyama, Takeshi Kawamura, Akinori
Kanai, Hidehiko Kawai, Junichi Iwakiri, Rin Liu, Manabu Maeshiro, Saruul
Tungalag, Masayoshi Tasaki, Mitsuharu Ueda, Kazuhito Tomizawa, Naoyuki
Kataoka, Takashi Ideue, Yutaka Suzuki, Kiyoshi Asai, Tokio Tani, Toshiya Inaba, Hirotaka Matsui. Leukemia 2022
Sequestration of RBM10 in Nuclear Bodies: Targeting Sequences and Biological
Significance. Ling-Yu Wang, Sheng-Jun Xiao, Hiroyuki Kunimoto, Kazuaki
Tokunaga, Hirotada Kojima, Masatsugu Kimura, Takahiro Yamamoto, Naoki Yamamoto,
Hong Zhao, Koji Nishio, Tokio Tani, Koichi Nakajima, Kishiko Sunami, Akira Inoue. International journal of
molecular sciences 22(19) 2021/9/29
Discovery, characterization and functional improvement of kumamonamide
as a novel plant growth inhibitor that disturbs plant microtubules. Takashi
Ishida, Haruna Yoshimura, Masatsugu Takekawa, Takumi Higaki, Takashi Ideue,
Masaki Hatano, Masayuki Igarashi, Tokio Tani, Shinichiro Sawa, Hayato Ishikawa. Scientific Reports 11(1) 2021/3/23