Yuji Yokouchi
Research highlight
For both plants and animals, genomes of a given species tend to be highly
diverse. Variations in human genomes contribute to differences in our appearances,
while in crops such diversities determine their qualities, and drive the
development of new strains. In order to study the such genomic diversities,
I developed the technique “allele-specific single-nucleotide substitution
One-SHOT” to induce single-nucleotide variations (SNV) in genomes, and
I’m interested in applying this technique to improve crop plants.
One of my research topics is the extension of fruit shelf life. Fruit ripening
is known to be induced by the hormone ethylene. In particular, fruits like
melon, peach and banana possess self-amplifying ethylene signaling pathways
such that they ripen especially fast. These fruits are known to release
charismatic fragrances when ripened, however they aren’t suited for long-distance
transports due to their exceptionally short shelf life.
My laboratory aims to delay the ripening process of these fruits by modifying
their ethylene signaling pathways, thereby extend their shelf life. This
breakthrough can potentially expand the regions where domestic produce
can be shipped internationally.
Résumé
1992.03: PhD, Graduate School of Science, Tohoku University.
1992.04 - 1993.03: JSPS Research Fellowships for Young Scientists, Research
Institute of Tuberculosis and Leprosy, Tohoku University.
1993.04 - 1998.03: Research assistant, Department of Molecular Biology,
Graduate School of Science, Nagoya University.
1998.04 - 2000.05: JSPS Overseas Research Fellowships, Harvard Medical
School.
2000.06 - 2011.03: Professor, Institute of Molecular Embryology and Genetics,
Kumamoto University.
2011.04 - 2014.10: Specially appointed professor, Institute of Resource
Development and Analysis, Kumamoto University.
2014.11 - 2020.09: Professor, Department of Research for Pluripotent Stem
Cells (endowed program), Fukushima Medical University.
2020.10 - 2024.03: Senior scientist, Institute of Molecular Embryology
and Genetics, Kumamoto University.
2024.04 - present: Specially appointed professor, International Research
Center for Agricultural & Environmental Biology, Kumamoto University.
Contact information
Tel:
(+81) 096-342-3558
Email: yokouchy(at)kumamoto-u.ac.jp
Address:
2-39-1 Kurokami, Chuo-ku,
Kumamoto, 860-8555 JAPAN
Kurokami South campus
Academic Commons Kurokami Building 2, Room 403.
PhD., Specially appointed professor
Genome editing technology
Department of Molecular Agriculture